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TAM-EVs may shift the AA catabolism to a COX1-dependent pathway instead of a COX2-dependent pathway, which may limit the tumor-promoting effects of certain prostaglandins (PGs) (Cianciaruso et al
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Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal N, et al
This means the ingredients may interact with medications
But Pliva never published the full results, so no outside researcher could check the work
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