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Fatigue Fatigue affects a subset of GLP-1 users, typically during the first four to eight weeks of treatment

This is framed as a timing issue rather than a permanent exclusion

At the center of this medical evolution are two powerhouses developed by Eli Lilly: Tirzepatide (commercially known as Mounjaro and Zepbound) and the highly anticipated pipeline drug, Retatrutide

Over the following weeks, patients often report smoother movement, improved tissue quality, and faster recovery from disc irritation, joint inflammation, or tendon strain

If youre cutting back on caffeine, do it gradually over a week or two rather than stopping suddenly, and drink extra water during this period

Without insurance, Wegovy pens start at $199 for the first two months, then increase to $349 per month