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Of note, in animals, the amino acid selenomethionine can be nonspecifically incorporated into proteins in place of methionine (2)

Symptoms associated with vitamin B12 deficiency include fatigue and lack of energy (due to anaemia), and depression, psychosis and even dementia

Giavalisco P, Li Y, Matthes A, Eckhardt A, Hubberten HM, Hesse H, Segu S, Hummel J, Khl K, Willmitzer L (2011) Elemental formula annotation of polar and lipophilic metabolites using 13 C, 15 N and 34 S isotope labelling, in combination with high-resolution mass spectrometry

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Schmidt, T

Studies have found 12 to 58% of ergogenic supplements contaminated, 30% containing incorrect amino acid sequences, and 65% exceeding safe endotoxin thresholds