Inclusion criteria were as follows: Age 65 years with T2DM (according to ADA guidelines), Body mass index (BMI) 24kg/m, with no prior use of GLP-1RA or DPP-4 inhibitors
GLP-1, or glucagon-like peptide-1, is a hormone that plays a major role in appetite regulation, digestion, and insulin release through a process called the incretin effect (1)
Antibody-dependent cellular phagocytosis in antiviral immune responses
Virology 12, 408421
In whats known as the SELECT trial, co-authored by UT Southwestern endocrinologist Ildiko Lingvay, M.D., M.P.H., M.S.C.S., 44% of patients using semaglutide lost more than 10% of their body weight within two years, and 11% of patients lost more than 20% more than enough to improve fertility
Gradual dose titration represents the cornerstone of minimizing adverse effects