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NPY also plays a role in the neuroimmune crosstalk as evidenced by the fact that it is also produced by immune cells in response to activation and as a result modulates several immunological functions such as chemotaxis, T cell differentiation, antigen presenting cell function, leukocyte migration, neutrophil respiratory burst, and phagocytosis by binding to different Y receptor subtypes

As of Aug

Nathan DM, Buse JB, Davidson MB, Heine RJ, Holman RR, Sherwin R, et al

Results showed that GLP-1R was expressed in primary HUVECs as detected by both immunofluorescence and western blot analyses

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They work by improving blood glucose control and promoting weight loss