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All constructs were cloned into a pcDNA3.1(+) vector backbone (ThermoFisher Scientific) and confirmed by sequencing analysis

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[2] AOD9401 was investigated separately in Zucker fatty rats and isolated adipose tissue

For TB-500, the agency has said it has identified no human exposure data for drug products containing the peptide and also highlighted potential risks associated with aggregation and impurities

However, there are established patterns based on clinical observations

Presented for research literature review only Bucur MP et al