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Regardless of source, every probiotic strain incorporated into food or supplement formulations must be supported by clear evidence of safety and efficacy

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PRRG4 regulates mitochondrial function and promotes migratory behaviors of breast cancer cells through the Src-STAT3-POLG axis

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Furthermore, immunostimulatory adjuvants including -glucans, medicinal mushrooms or high-dose probiotics can also in immuno-compromised patients induce opportunistic infections, sepsis or bacteremia especially if the integrity of gut barrier is compromised by chemotherapy-induced mucositis (206)