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A majority of cats that require B12 supplementation, especially for GI disease, will require therapy for life

Conclusion Administering your own B12 injections at home may seem daunting at first, but with proper preparation and practice, it can become a straightforward and empowering part of managing your health

While this represents a reasonable duration for clinical trials, it provides limited information about safety with years-long continuous use

So, while the idea that B12 injections cause weight gain might be a popular rumor, current evidence indicates that a vitamin B12 deficiency is unlikely to affect your weight directly in terms of gain

[18] Lactation studies demonstrate that maternal injections modestly elevate breast-milk B12 concentrations without adverse infant outcomes, supporting compatibility with breastfeeding while underscoring the need for maternal repletion to prevent neonatal deficiency

That means faster, more reliable absorption than oral supplements