Berchtold L, Crowe LA, Friedli I et al (2020) Diffusion magnetic resonance imaging detects an increase in interstitial fibrosis earlier than the decline of renal function
In the face of vitamin B 12 deficiency, conversion of methylmalonyl-CoA to succinyl-CoA cannot take place, which results in accumulation of methylmalonyl-CoA and aberrant fatty acid synthesis
doi: 10.1210/jcem-24-10-1076 5 McintyreNHoldsworthCDTurnerDS
Rapid weight loss can be associated with reductions in bone mineral density, which is of particular relevance to perimenopausal and postmenopausal women who are already at increased risk of osteoporosis
Mean body weight at randomization (Week 20) was 96.1 kg and mean BMI at randomization (Week 20) was 34.4 kg/m 2
Then theres the next-generation GLP-2s that promise even greater benefits, with easier administration and broader therapeutic effects, further capturing the attention of reinsurers and underwriters