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In contrast, the passive diffusion process of B 12 absorption normally a very small portion of total absorption of the vitamin from food consumption may exceed the haptocorrin- and IF-mediated absorption when oral doses of B 12 are very large, with roughly 1% efficiency
Stem Cells Dayt Ohio 33:13201332 Jia L et al (2019) Vitamin B12 inhibits -synuclein fibrillogenesis and protects against amyloid-induced cytotoxicity
Disadvantages involve benefit decline during off periods requiring acceptance of fluctuation, complexity planning and tracking cycles, uncertainty about optimal timing and duration for individual responses, and potential for forgetting to restart after extended breaks
Reported mild side effects include nausea, dizziness, and irritation at the injection site, and the compound is generally well tolerated with minimal side effects in research settings