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FDA in 1997 in the context of pediatric growth hormone deficiency, and the original product was later discontinued for commercial reasons around 2008
Redox Signaling 14 (8), 14491465
Even for peptides that are not specifically light-sensitive, minimizing light exposure is good practice
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Regardless, it is difficult to compare any of these studies, because of different levels of hypoxia, performance protocols and states of hypoxic adaptation, as well as several of the studies being potentially under-powered to detect a performance difference ( n 7 [131, 134, 135])