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Further analysis of data beyond 6 months showed that reductions in HbA1c and weight continued over time during the 3-year follow-up

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Statistics JMP Pro software version 15.0.0 (SAS Institute Inc., Cary, NC, USA) or GraphPad Prism7.05 was used for the statistical analysis

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A 60% decline over four decades

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Freezing causes irreversible structural changes to the peptide that cannot be detected by visual inspection

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