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At times the needle can hit a small blood vessel causing a small amount of bleeding under the skin This causes a bruise to appear which resolves over a few days

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All the above methods have been systematically validated

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Each category works through a different mechanism, carries a different level of clinical evidence, and comes with its own cost and safety considerations, so understanding the distinction matters before choosing one

1) Gastrointestinal Disturbances Reported Effects: Nausea Abdominal discomfort Stomach cramping Occasional diarrhea Gastrointestinal symptoms are among the most commonly reported early adverse effects