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To address systemic uptake limitations, researchers have explored dendrimer-conjugated Epitalon

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Insurance coverage negotiations will begin, likely with initial restriction to patients with BMI above specific thresholds and documented comorbidities, mirroring the coverage battles that followed Wegovy and Zepbound's approvals

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Metformin, another common treatment, sees adherence rates decline from 57.7% at three months to just 31.2% by the end of 12 months

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