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When 5GABA-A receptor PAM, MP-III-022 was used in rats in the VPA model, an increase in mRNA level of KCC2 was observed only in females treated with a dose of 1 mg/kg, while the mRNA level of Gabra5 and Nkcc1 remained unchanged across doses and animal sexes [58]
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During lengthy activities, fat is used as a helper fuel as its composition allows for large amounts of energy to be produced over time (Spriet & Randell 2020)
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