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These cytokines may increase the activity of immune cells, such as mast cells, which can affect nearby nerves and contribute to pain (Anaf 2006)
These developments underscore the importance of GLP-1RAs in modern therapeutics
a ) the carboxyl group makes electrostatic interactions with Arg439 and Arg929 of IRAP and b ) phenyl ring of the phenylacetic acid group makes pi-stacking interactions with Tyr961
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