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Pigmentation is the result of increased melanin production due to prolonged UV exposure
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Tirzepatide appears to activate GIPR stronger than GLP1R in cell systems with high levels of both gene expressions [20]
This heterogeneity is partly genetic: mouse strains with polymorphisms in the Slc6a4 gene (encoding the 5-HT transporter) exhibit divergent responses to ethanol, with short-allele carriers showing heightened vulnerability to depression-like phenotypes
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Body image improvement follows weight loss but often lags behind
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