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Nanomedicine platforms, engineered with precise control over size, surface chemistry, and drug release kinetics, can enhance the bioavailability and tumor-specific delivery of immunotherapeutic agents while minimizing systemic toxicity ( To distinguish from the broadly discussed literature on sarcoma nanomedicine, the main contribution of this mini-review is specifically focused on the precise intersection of engineered nanoplatforms and translational barriers
Frias JP et al
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Studies have examined TB-500s effects on keratinocyte migration and re-epithelialisation, dermal fibroblast activation and matrix deposition, angiogenic vessel ingrowth into wound beds, inflammatory cell recruitment and resolution, and the overall kinetics of wound closure in pre-clinical models
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