Another natural compound, trigonelline, a methylated form of nicotinic acid, is a newly discovered NAD + precursor able to increase NAD + in multiple species, with preclinical implications for use in sarcopenia, and for muscle and cognitive decline in aging 124,130,131
Dihexa, a small molecule peptide, is particularly notable for its ability to penetrate the brain and facilitate the repair and growth of neurons, a critical aspect in addressing cognitive decline
twofold, P = 0.11
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B., Chrysanthou, E., Schwaeble, W
(PubMed) Hedin U, Roy J, Tran PK