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These two domains are adjacent to each other on the enzyme, and together form the active site of the GST where the redox reaction occurs

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It can make a tissue environment less hostile to conception by reducing inflammation and increasing perfusion

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Its sequence is Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (abbreviation: WAGGDASGE)

One patient with severe knee and shoulder instability, for instance, received prolotherapy a few times per year over more than a decade and was able to continue working and stay active without recurrent dislocations