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Upon binding to its receptor complex, IL-22 activates the JAK/STAT signaling pathway, promoting hepatocyte regeneration and repair [149, 150]

A., Zavarzina, N

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Work at Rothamsted Research is supported via the 20:20 Wheat Programme (BBS/E/C/00005202) funded by the UK Biotechnology and Biological Science Research Council

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They act on different appetite pathways cagrilintide is a long-acting amylin analog, while tirzepatide is a dual GIP/GLP-1 receptor agonist which is the theoretical reason researchers discuss pairing them