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All experimentation must remain within the confines of legal in-vitro or ex-vivo frameworks until comprehensive toxicology and regulatory review justify progression to clinical testing

Data sources and search strategy Systematic searches were conducted in PubMed, Medline, Embase, the Cochrane Center Register of Controlled Trials for Studies, and Clinicaltrials.gov last updated on March 8, 2024

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Sets of 1-5 reps with very heavy loads are effective for strength development but carry higher injury risk during a caloric deficit when recovery is compromised

Diagnosis involves a detailed medical history, sometimes followed by urine or blood antibody testing to confirm the overgrowth

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