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We also note that when spontaneously diabetic NOD mice become diabetic their spleens shrink to a tiny size, whereas the spleen size remains normal in BCG-treated NOD 43

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Thus, GLP-1 and GLP-1RAs have a beneficial effect on neurogenesis, potentially having translational significance, since these compounds can have a positive effect in various mental disorders characterized by defects in neurogenesis (including depressive disorders and neurocognitive disorders)

Abstract Previous studies have explored the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in reducing cardiovascular events in type 2 diabetes

Long-term safety is monitored by clinicians

Together these studies underscore the importance of miRNAs in human beta cell function and point to their implication in type 2 diabetes