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Chronic low-grade inflammation contributes significantly to skin aging through constant breakdown of structural proteins

Interestingly, the findings showed that spermidine improves skin health indirectly by reshaping the skin microbiome and restoring microbial functions that protect the epidermis

These are interesting results because children with cystic fibrosis often suffer from growth impediment, so improvements in these areas suggest possible application for treatment of the condition

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These pathways may involve both receptor-dependent and receptor-independent mechanisms related to metabolic regulation

That distinction matters, and prescribers should be clear-eyed about it