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Beyond effects on hard renal endpoints, empagliflozin also resulted in a reversible eGFR dip after approximately 4 weeks of therapy

This ratio works best for researchers in later titration phases who need 1 mg or higher per injection

But in a sensitivity analysis, the authors see what happens if they just treat people as if they were taking the drug for the entire year once they had it prescribed, and the results, while not as dramatic, were broadly similar

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Loss of muscle mass and strength not only impairs mobility and quality of life, but also worsens insulin resistance, accelerates cardiometabolic decline and increases mortality risk