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Next-generation agents, including triple agonists such as retatrutide, extend beyond GLP-1 and GIP to include glucagon receptor activation, introducing a new dimension of energy expenditure and metabolic regulation

Increased Bleeding Risk : Since both medications have side effects that can increase the risk of bleeding, using them together may heighten this risk

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Additionally, individuals without insurance coverage or with inadequate coverage may face higher retail prices for these medications

After obtaining the MS/MS scan data of the 168 MFs (Supplementary Table 2), compound identification was performed using the METLIN database

Maintaining Weight Loss and Preventing Regain One of the most critical aspects of any effective weight loss strategy is the ability to sustain results