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SLC7A11-, GCLC-, and GSS-overexpressing plasmids were purchased from Origene (USA)
In preclinical studies, the peptide activated melanocortin receptors in the medial preoptic area, leading to increased dopamine signaling and enhanced sexual motivation
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Conclusion Being a central regulator of intracellular redox homeostasis, the Trx system is markedly involved in autophagy, ferroptosis and apoptosis regulation via its electron transfer function and diverse signaling pathways
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