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Extrinsic aging of the skin involves a variety of factors and a cascade of events, where oxidative stress leads to inflammation, which in turn leads to more oxidative stress (Fig

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Nowadays, it can even be grown to have higher levels of THC, which makes its effects even stronger

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Yao L, Chen H, Wu Q, Xie K

Walker RF, Codd EE, Barone FC, Bhatt RK, McAuliff J, Campbell GF