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381 PF1801 activates these receptors, initiating a series of biological responses that influence the inflammatory state of muscle cells, thereby alleviating inflammation

However, it is not recommended for use in newborns or premature infants, as neonates lack the metabolic capacity to process benzyl alcohol safely a contraindication explicitly noted in FDA guidance on benzyl alcohol toxicity in neonates

No cause has been proven, but experts recommend using the lowest dose when needed and focusing on good prenatal care

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