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Most patients find these side effects are mild to moderate in severity and tend to diminish significantly after the first few weeks as the body adjusts to the medication

Instead, it enters the nerve tissues near the spinal cord and brain, where it stays dormant for years or even decades

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Regular monitoring throughout the 48 weeks captured not just weight changes but comprehensive metabolic markers, safety signals, and quality of life measures

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95, Elsevier, 2022, pp