Reestablishing the cellular metabolic homeostasis in SARS-CoV-2 infection and COVID-19 disease especially in the lungs, could become paramount to balance altered innate and adaptive immunity and cell function and reduce morbimortality (Hsu et al., 2022
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Glutathione conjugates with acetaldehyde via glutathione S-transferase (GST), forming a mercapturic acid derivative that the kidneys excrete
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It was supposed that this GSTU enzyme contributed to a balance between growth and defense responses (Kao et al., 2016)