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[7] The last, a condition in which the pressure in the portal vein is markedly increased, leads to esophageal varices as well as splenomegaly and ascites

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9 GSH can be depleted intracellularly either by forming a direct complex with an electrophilic agent (accomplished investigationally by agents such as bromobenzene or diethyl maleate) via inhibition of synthesis, or by subjecting cells to oxidant stress