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In SURMOUNT-1 , a 72-week Phase 3 double-blind trial in 2,539 adults with obesity (or overweight with a complication) but without diabetes, once-weekly tirzepatide produced mean weight changes of 15.0% (5 mg), 19.5% (10 mg), and 20.9% (15 mg) versus 3.1% with placebo, with 5057% of participants on the higher doses losing at least 20% of body weight
The HRTS portfolio aims to be broadly exposed to breakthrough innovation and to balance risk profiles
Similar concentration considerations apply to those using the tirzepatide unit conversion charts or calculating doses from the tirzepatide dosing tables for weight loss
C., Williams, K
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