Limited Product Level Regulatory Review Compounded medications do not undergo FDA approval for finished products, unlike commercial drugs
Without enough B12, these cells can become large and misshapen (megaloblastic anaemia), reducing oxygen flow to your brain and muscles, causing fatigue and weakness

Ozempic 0.25 mg or 0.5 mg dose (2 mg/3 mL subcutaneous pen injector) NDC: 0169-4181-13 Days supply: Sample/initial (42 days) 1-month supply (28 days) Intent of prescription: Sample or initial prescription for new starts 1-month prescription for maintenance on 0.5 mg For patients with T2D and CKD, increase to the recommended maintenance dose of 1 mg after at least 4 weeks on 0.5 mg Strength: 2 mg per 3 mL (0.68 mg/mL) Dosage form: Solution SIG: Sample or initial Rx: Inject 0.25 mg SUBQ once weekly for 4 weeks, then 0.5 mg SUBQ once weekly for 2 weeks Maintenance Rx: Inject 0.5 mg SUBQ once weekly for 4 weeks Dispense quantity: 3 mL Dispense quantity unit of measure: mL ONLY Needles: 6 included Number of boxes: 1 box Ozempic 0.25 mg or 0.5 mg dose (2 mg/3 mL subcutaneous pen injector) NDC: 0169-4181-13 Days supply: 3-month supply (84 days) Intent of prescription: 3-month prescription for maintenance on 0.5 mg For patients with T2D and CKD, increase to the recommended maintenance dose of 1 mg after at least 4 weeks on 0.5 mg Strength: 2 mg per 3 mL (0.68 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 0.5 mg SUBQ once weekly for 12 weeks Dispense quantity: 9 mL Dispense quantity unit of measure: mL ONLY Needles: 18 included Number of boxes: 3 boxes Ozempic 1 mg dose (4 mg/3 mL subcutaneous pen injector) NDC: 0169-4130-13 Days supply: 1-month supply (28 days) Intent of prescription: 1-month prescription for maintenance on 1 mg Strength: 4 mg per 3 mL (1.34 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 1 mg SUBQ once weekly for 4 weeks Dispense quantity: 3 mL Dispense quantity unit of measure: mL ONLY Needles: 4 included Number of boxes: 1 box Ozempic 1 mg dose (4 mg/3 mL subcutaneous pen injector) NDC: 0169-4130-13 Days supply: 3-month supply (84 days) Intent of prescription: 3-month prescription for maintenance on 1 mg For patients with T2D and CKD, increase to the recommended maintenance dose of 1 mg Strength: 4 mg per 3 mL (1.34 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 1 mg SUBQ once weekly for 12 weeks Dispense quantity: 9 mL Dispense quantity unit of measure: mL ONLY Needles: 12 included Number of boxes: 3 boxes Ozempic 2 mg dose (8 mg/3 mL subcutaneous pen injector) NDC: 0169-4772-12 Days supply: 1-month supply (28 days) Intent of prescription: 1-month prescription for maintenance on 2 mg Strength: 8 mg per 3 mL (2.68 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 2 mg SUBQ once weekly for 4 weeks Dispense quantity: 3 mL Dispense quantity unit of measure: mL ONLY Needles: 4 included Number of boxes: 1 box Ozempic 2 mg dose (8 mg/3 mL subcutaneous pen injector) NDC: 0169-4772-12 Days supply: 3-month supply (84 days) Intent of prescription: 3-month prescription for maintenance on 2 mg Strength: 8 mg per 3 mL (2.68 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 2 mg SUBQ once weekly for 12 weeks Dispense quantity: 9 mL Dispense quantity unit of measure: mL ONLY Needles: 12 included Number of boxes: 3 boxes Saving Ozempic as a favorite in the EHR as a favorite in the EHR If your EHR allows you to save your frequently used prescriptions to a "favorites" list, be sure to add Ozempic pen for quicker access

Recent advances in basic medical research and clinical therapeutics have optimized the application of glucagon-like peptide-1 (GLP-1), establishing it as a cornerstone incretin based therapy for T2DM management
Nausea is particularly common during the initial weeks of treatment and after dose increases
Below, well walk through the steps, from the initial dose to dose increases, and what to do if you miss a dose