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Sci Rep 2021;11(1):13361

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While sex differences in expression are not apparent in these regions, elevated aromatase levels have been reported in the hypothalamusspecifically in the POA and VMNof male animals, suggesting regulation by circulating testosterone, which is subsequently converted to estradiol (E2) (Gillies and McArthur, 2010)

Its true that GLP-1 medications are administered via injection