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The evidence suggests that without deliberate intervention, patients on GLP-1 therapies may lose a significant proportion of their weight from lean mass, a finding that has considerable implications for long-term metabolic health, physical function, and the sustainability of results. Why Muscle Mass is Not a Cosmetic Concern When patients hear the phrase muscle loss, they frequently interpret it through an aesthetic lens

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Hepatology 40 (6), 13221332 (2004)

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