This may be because they calm overactive immune responses, including in people with Mast Cell Activation Syndrome (MCAS)a condition where the bodys allergy cells overreact
These older medications produce less dramatic weight loss compared to semaglutide and tirzepatide, which supports the theory that the rate and magnitude of weight loss, rather than the GLP-1 receptor activation itself, drives most of the hair shedding
10.1053/j.gastro.2009.08.042 114
Platelet-derived growth factor BB mediates the tropism of human mesenchymal stem cells for malignant gliomas
However, because glucagon-like peptide-1 receptor agonists work to slow gastric emptying, a safety concern has been raised in patients undergoing deep sedation or general anesthesia regarding gastric aspiration, and considering their long half-life in the blood, they are difficult to manage in the perioperative period
Chrousos, G