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Free Radic Biol Med 65:15481556 Brigelius-Floh R, Banning A, Schnurr K (2003) Selenium-dependent enzymes in endothelial cell function

The role of gut microbiota on insulin resistance

The medication was first developed by Novo Nordisk and has received multiple FDA approvals

Tirzepatide activates both GLP-1 and GIP receptors, while semaglutide only targets GLP-1 receptors

GLP-1 receptor agonists like semaglutide 2.4 mg (Wegovy) are available through NHS specialist weight management services (Tier 3/4) for eligible patients meeting NICE TA875 criteria

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