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Description Product Information Product Name: Retatrutide (LY3437943), 99.70% purity peptide (TFA removed) Description: Retatrutide is the first triple agonist peptide targeting the Glucagon, GLP-1, and GIP receptors (3G) , the EC50 values are 5.79 nM, 0.0643 nM, and 0.775 nM respectively [1]
The manufacturer adopted an unconventional pricing model, setting the price at 50% less than the eculizumab (standard of care) list price, alongside unusually prominent direct-to-consumer (DTC) marketing in a market where patient awareness had historically been near zero
This also led its drug manufacturer, Novo Nordisk, to get a higher dose of the active ingredient semaglutide FDA-approved for weight management under the brand name Wegovy
PMC 4309183
The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas
Key Benefits of Semaglu Semaglutide Pre-filled Injection Pen Semaglutide helps lower blood glucose in a glucose-dependent way
