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Animal studies indicate fetal growth restriction, ossification delay, skeletal variants, and reduced maternal weight gain, though more recent human evidence, including a 2024 cohort of 938 pregnancies, suggests no increased risk of major congenital malformations compared with insulin

If they don't have it, their risk of getting diabetes goes down

These effects contribute to improved glycemic control and a decrease in blood sugar levels

If gastrointestinal side effects are particularly troublesome, your healthcare provider may consider slowing down the dose escalation schedule or temporarily reducing to a previously tolerated dose

The role of short chain fatty acids in appetite regulation and energy homeostasis

LC3A/B-I is converted to LC3A/B-II (Kouno et al., 2012)