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One very elegant design is to use a form of B12 that can be detected by rather sophisticated methodologies in a blood sample
Yuan H, Li X, Zhang X, Kang R, Tang D (2016a) CISD1 inhibits ferroptosis by protection against mitochondrial lipid peroxidation
doi:10.1002/jcp.25328
But more research is needed
Its especially good at holding hands with heavy metals to support removing them from the body, as part of the bodys natural heavy metal detox process
In concordance with the results of the uptake experiments, the image analysis also verified that the cellular internalization of targeted nanocarriers was significantly higher (2.4-times elevation for 3-PLG-dopa-A-GSH
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