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Treatment with FOXO4-DRI led to the nuclear exclusion of active Ser15-phospho-p53 in senescent cells

Understanding this fundamental distinction clarifies their complementary roles in oxidative stress management

J Clin Invest 40:19671977 Voogel AJ, Koopman MG, Hart AA, van Montfrans GA, Arisz L (2001) Circadian rhythms in systemic hemodynamics and renal function in healthy subjects and patients with nephrotic syndrome

This process relies on the recruitment of co-regulatorssuch as co-activators (SRC-1, CBP/p300) or co-repressors (SMRT, NCoR)which modulate chromatin accessibility

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