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Loss of Muscle Mass: Ongoing calorie restriction may result in loss of muscle mass which will be detrimental to overall health and maintaining weight loss after discontinuation

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Mol Vis 19:17601768 Leng B, Li C, Sun Y, Zhao K, Zhang L, Lu ML, Wang HX (2020) Protective effect of Astragaloside IV on high glucose-induced endothelial dysfunction via inhibition of P2X7R dependent P38 MAPK signaling pathway

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In pregnant sheep, fluoxetine treatment has also been shown to decrease prenatal circulating calcium levels, an effect that was transient and disappeared post-treatment

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