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Key information extracted from each included study encompassed study characteristics (first author, year of publication, study design, sample size, and participant demographics), intervention details (dosage, route of administration, treatment duration, and control conditions), and primary outcomes related to lipid profiles, specifically TC, TG, HDL, LDL, and VLDL

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Clinically significant fluid retention could theoretically alter the volume of distribution of apixaban, though no study has quantified this effect

But heres why the comparison isnt straightforward: these two drugs target completely different hormonal systems

Later that year, in November, Dar et al