Li, P., Yin, Y., Li, D., et al
Magnesium works through osmotic draw and mild smooth muscle stimulation, which complements natural peristalsis without creating dependency but it doesnt address the root cause, which is redox signaling disruption from excessive gut glutathione exposure
Liposomal or IV forms tend to have better absorption and are also considered safe when used appropriately
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a study in rats of a single-tablet combination demonstrated that including methionine could minimize liver toxicity (measured by serum ALT and AST) at therapeutic (100 mg/kg) and highly toxic (1000 mg/kg) acetaminophen doses (Iyanda 2010)
Mater Today Bio 32:101794