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This is usually only recommended for individuals on high maintenance doses who wish to minimize the volume of the injection

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Notably, the authors suggested that semaglutide may reduce de novo collagen synthesis without causing degradation of pre-existing collagen fibers [29], implying that semaglutide may not improve existing fibrosis, but it may prevent the initiation and progression of fibrosis, which, however, needs other more focused studies to be definitively demonstrated

it also can protect against life-threatening cardiovascular events

These give you the most muscle-preservation stimulus per set, which matters when total volume is reduced

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