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This less conserved domain, compared to the N-terminal domain, notably contains a well-conserved N-capping box (S/TXXD) including the S/T N-cap residue (Figure 3A) and a hydrophobic staple motif located at the N-terminal part of 6 helix

It appears to rejuvenate aging cells by restoring youthful gene expression patterns

In recent years, skin AGE measurement can be performed with specially developed ultrasonic devices as an indicator of increased oxidative damage

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An article cited in Journal of Cancer Science and Therapy indicated that glutathione deficiency leads to increased levels of oxidative stress, which might lead to cancer

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