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High expression and activation of SREBPs have been reported in various cancers and have been shown to promote tumor growth (Cheng et al., 2018)

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Purpose-built for physicians Benefits of GLP-1s outweigh harms when patients achieve 10% weight loss Key takeaways: Although achieving 10% weight loss outweighed the harms of GLP-1 receptor agonists, 5% weight loss did not

Ferroptosis signaling promotes functional recovery after sciatic nerve injury in mice Although axonal fusion after injury has not been directly demonstrated in vertebrates to date, there is extensive evidence showing that axonal fusion-like mechanisms can be induced to promote nerve repair in mammals, including humans 1

specifically examined patients with MASLD cirrhosis and type 2 diabetes, finding that GLP-1 receptor agonist initiation was linked to reduced risk of unfavorable liver outcomes including hepatic decompensation events and mortality from any cause (aHR: 0.78, 95%CI: 0.68-0.90) relative to non-users, suggesting potential benefits even in advanced liver disease populations [58]

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