Hausner H, Derving Karsbl J, Holst AG, et al
36-38 Low rates of hypoglycemia have been reported in clinical trials of SGLT-2 inhibitors, except in patients receiving therapy with background insulin or insulin secretagogues
1 Reflecting back on our case: the pharmacist explains to Mike that Bella needs two doses after age 1 to ensure immunity to measles
Manufacturing delays: Scaling up production of a triple-agonist peptide is complex
196 In the tumor environment, succinate could be produced and released by tumor cells, and via interacting with succinate receptor 1 to activate phosphoinositide-3-kinase/protein kinase B pathway and upregulate HIF-1, inducing macrophage polarization, and enhancing tumor cell metastasis
These healthspan improvement findings have profound implications for longevity research, development of geroprotective therapies, and understanding how senescent cell accumulation contributes to the functional decline characteristic of biological aging