In STEP 1, participants without diabetes who received 2.4mg of semaglutide weekly lost an average of 14.9% of their body weight over 68 weeks
REDEFINE 4 enrolled 809 adults and was open-label, meaning participants and clinicians knew which drug each person was on
World J Diabetes (2015) 6(15):1296308.10.4239/wjd.v6.i15.1296 112 PaisRZietekTHaunerHDanielHSkurkT
Precautions for Using the GLP-1 program The GLP-1 program should be used by one individual only
Glucose Stimulated Insulin Secretion (GSIS) For in vitro static GSIS, digestion and islet isolation was performed as previously described 1, 15, 16 for each condition
Herbal and nutritional supplements Certain herbs and supplements can support the mechanisms of GLP-1 drugs: Berberine: Helps regulate blood sugar and supports gut health Cinnamon: Enhances insulin sensitivity Apple cider vinegar: Can reduce post-meal glucose spikes Adaptogens: Maca, Rhodiola, and Holy Basil help modulate stress and hormonal balance Detoxification and environmental health Reducing exposure to endocrine-disrupting chemicals in plastics, pesticides, and personal care products is vital for your hormonal and metabolic health and weight loss